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8-iso-13,14-dihydro-15-keto Prostaglandin F2α
品牌:Cayman
货号:16380-1 mg 规格:1 mg 目录价:¥14378
货号:16380-100 µg 规格:100 µg 目录价:¥1680
货号:16380-50 µg 规格:50 µg 目录价:¥1134
货号:16380-500 µg 规格:500 µg 目录价:¥7742
产品详情
产品名称:
8-iso-13,14-dihydro-15-keto Prostaglandin F2α
别名:
8-iso-13,14-dihydro-15-keto PGF2α
产品描述:
8-iso-13,14-dihydro-15-keto Prostaglandin F2α (8-iso-13,14-dihydro-15-keto PGF2α) is a metabolite of the isoprostane, 8-isoprostane (8-iso PGF2α), in rabbits, monkeys and humans.{6907} 8-iso PGF2α is a PG-like product of non-specific lipid peroxidation.{320} In both humans and monkeys, exogenously infused 8-isoprostane is converted primarily to metabolites having 2 or 4 carbon atoms removed from the top side chain by β-oxidation.{6907} A similar pattern is observed when tritiated 8-isoprostane is infused into rabbits.{11209} Early in the infusion (within 10 minutes) 8-iso-13,14-dihydro-15-keto PGF2α was a significant component of the metabolite profile, which was comprised mostly of dinor 8-isoprostane metabolites. 8-iso-13,14-dihydro-15-keto PGF2α weakly inhibits the U-46619 or collagen-induced aggregation of human platelets, although a number of the E-series isoprostanes are much more potent in this assay.{11145}
保存温度:
-20
运输温度:
-20
预期分子量:
354.5
产品形式:
A solution in methyl acetate
有效期:
730
纯度:
≥98%
CAS号:
191919-02-5
分子式:
C20H34O5
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