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13,14-dihydro-16,16-difluoro Prostaglandin E1
品牌:Cayman
货号:9000405-1 mg 规格:1 mg 目录价:¥5194
货号:9000405-100 µg 规格:100 µg 目录价:¥672
货号:9000405-5 mg 规格:5 mg 目录价:¥22582
货号:9000405-500 µg 规格:500 µg 目录价:¥2940
产品详情
产品名称:
13,14-dihydro-16,16-difluoro Prostaglandin E1
别名:
15-hydroxy Lubiprostone
产品描述:
Prostaglandin E1 (PGE1) is produced by the metabolism of dihomo-γ-linolenic acid (DGLA) by the cyclooxygenase pathway. PGE1 inhibits platelet aggregation (IC50 = 40 nM){960,4165} and increases vasodilation. 13,14-dihydro-16,16-difluoro PGE1 is an analog of PGE1. 13,14-dihydro PGE1 is a biologically active metabolite of PGE1, inhibiting platelet aggregation with comparable potency to the parent compound.{2126,4165} The addition of two electron-withdrawing fluorine atoms, which should stabilize the molecule against hydrolytic cleavage, may be expected to delay degradation in vivo.{17623}
保存温度:
-20
运输温度:
-20
预期分子量:
392.5
产品形式:
A solution in methyl acetate
有效期:
730
纯度:
≥98%
CAS号:
475992-30-4
分子式:
C20H34F2O5
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