13,14-dihydro-15-keto Prostaglandin E2-d4-前列腺素-深圳九游会j9网站首页有限公司

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13,14-dihydro-15-keto Prostaglandin E2-d4

品牌：Cayman

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说明书

折扣/货期

货号：10010606-100 µg	规格：100 µg	目录价：￥5768
货号：10010606-25 µg	规格：25 µg	目录价：￥1624
货号：10010606-50 µg	规格：50 µg	目录价：￥3066

产品详情

产品名称:

13,14-dihydro-15-keto Prostaglandin E2-d4

别名:

13,14-dh-15-keto PGE2-d4|13,14-dihydro-oxo-PGE2-d4|PGEM-d4

产品描述:

13,14-dihydro-15-keto Prostaglandin E2-d4 (13,14-dihydro-15-keto PGE2-d4) is intended for use as an internal standard for the quantification of 13,14-dihydro-15-keto PGE2 (Item No. 14650) by GC- or LC-MS. 13,14-dihydro-15-keto PGE2 is a metabolite of PGE2 (Item No. 14010) and the primary PGE2 metabolite in plasma.{182,2777} It is formed from PGE2 via a 15-keto PGE2 intermediate by 15-oxo-PG Δ13 reductase.{2777} Unlike PGE2, 13,14-dihydro-15-keto PGE2 does not bind effectively to the PGE2 receptors EP2 and EP4 expressed in CHO cells (Kis = 12 and 57 µM, respectively) or induce adenylate cyclase activity in the same cells (EC50s = >18 and >38 µM, respectively). Levels of 13,14-dihydro-15-keto PGE2 are increased in the plasma of women in the third trimester of pregnancy and in women during and immediately after labor and delivery.{64194} Levels of 13,14-dihydro-15-keto PGE2 levels are decreased in tumor tissue compared to adjacent non-cancerous tissue isolated from patients with non-small cell lung cancer (NSCLC).{64195}

保存温度:

-20

运输温度:

-20

预期分子量:

356.5

产品形式:

A solution in methyl acetate

有效期:

730

纯度:

≥99% deuterated forms (d1-d4)