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折扣/货期| 货号：12410-1 mg | 规格：1 mg | 目录价：￥994 |
| 货号：12410-10 mg | 规格：10 mg | 目录价：￥7756 |
| 货号：12410-5 mg | 规格：5 mg | 目录价：￥4382 |
产品详情
产品名称:
11-deoxy-11-methylene Prostaglandin D2
别名:
11-deoxy-11-methylene PGD2
产品描述:
Prostaglandin D2 (PGD2; Item No. 12010) is one of the five primary enzymatic prostaglandins derived directly from PGH2 (Item No. 17020). PGD2 is produced abundantly in the CSF by the lipocalin-type PGD synthase, and in the periphery by myeloid cells including mast cells and basophils by a second, leukocyte-type PGD synthase.{9588} PGD2 is chemically unstable, and its use and analysis is complicated by its short in vivo half-life. 11-deoxy-11-methylene PGD2 is a novel, chemically stable, isosteric analog of PGD2 wherein the 11-keto group is replaced by an exocyclic methylene. In the PGE series, the analogous modification leads to a stable, somewhat less potent agonist which embodies the same uterine stimulant and cervical ripening activities as the parent prostaglandin.{7894} However, 11-deoxy-11-methylene PGD2 has been reported by one group to be essentially without agonist activity on human platelets, a DP1 receptor assay.{11175} The CRTH2-receptor actions of 11-deoxy-11-methylene PGD2 are not yet reported.
保存温度:
-20
运输温度:
-20
预期分子量:
350.5
产品形式:
A solution in methyl acetate
有效期:
730
纯度:
≥98%
CAS号:
100648-29-1
分子式:
C21H34O4
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