Zinc-alpha-2-glycoprotein (human) Matched Pair Detection Set-抗体对-ELISA_抗体_蛋白_核苷酸

首页产品中心抗体对

Zinc-alpha-2-glycoprotein (human) Matched Pair Detection Set

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-46B-0008-KI01

规格：1 Set

目录价：￥7800

产品详情

产品名称:

Zinc-alpha-2-glycoprotein (human) Matched Pair Detection Set

别名:

Zn-alpha-2-GP; Zn-alpha-2-Glycoprotein; ZAG; ZA2G; AZGP1; ZNGP1

产品描述:

Zinc-alpha-2-glycoprotein (ZAG), first identified in the 1960s, derives its name from its precipitation from human plasma upon the addition of zinc salts. ZAG has since been found in secretory epithelial cells and in a range of body fluids. ZAG is identical to a lipid mobilizing factor isolated from the urine of patients with cancer cachexia and stimulates lipolysis in in vitro and in vivo experiments. Due to its expression in, and secretion from adipocytes, ZAG is considered an adipokine. Recently the clinical significance of ZAG has been clarified. ZAG expression in adipocytes is inversely related to fat mass, thus it is intimately involved in the maintenance of body weight in mice and humans. Epidemiological studies have uncovered an association between ZAG and plasma cholesterol. The non-synonymous single nucleotide polymorphism rs4215 in ZAG is associated with plasma cholesterol and obesity. Structurally ZAG possesses a class I major histocompatibility complex (MHC) protein fold. It is distinct from other members of this protein family in that it is soluble, rather than being anchored to plasma membranes, and it associates with prolactin inducible protein rather than beta2-microglobulin. Similar to peptide antigen-presenting class I MHC molecules, ZAG possesses an open apical groove between its alpha1 and alpha2 domain helices.

靶标/特异性:

Detects human Zinc-alpha-2-glycoprotein. Does not detect mouse Zinc-alpha-2-glycoprotein.

保存温度:

-20°C

运输温度:

BLUE ICE

有效期:

Stable for at least 1 year after receipt when stored at -20°C.

产地:

瑞士

灵敏度:

100 pg/ml