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    细胞因子报告基因细胞/趋势因子测试细胞

    2023-02-28
    浏览次数: 50

    细胞因子与免疫系统细胞相互作用可调节宿主对于疾病和感染的反应,并介导正常的细胞过程。InvivoGen提供针对不同细胞因子(干扰素、白细胞介素、TNF和TGF)信号通路的报告基因细胞。所有细胞系的生物活性均经过严格的功能测试分析。另外,InvivoGen也提供一系列细胞因子报告基因细胞,可用于研究在更多严重感染病例中,如SARS-CoV-2引发的高度炎症反应的通路。


    细胞系产品名称表达系统报告系统货号
    INTERFERONREPORTERCELLS
    B16(mouse)B16-Blue™IFN-α/βMousetypeIIFNs(JAK/ISGF3pathway)SEAPbb-ifnt1
    B16-Blue™IFN-γMousetypeIIIFN(JAK/STAT-1pathway)SEAPbb-ifng
    HEK293(human)HEK-Blue™IFN-α/βHumantypeIIFNs(JAK/ISGF3pathway)SEAPhkb-ifnab
    HEK-Blue™IFN-γHumantypeIIIFN(JAK/STAT-1pathway)SEAPhkb-ifng
    HEK-Blue™IFN-λHumantypeIIIIFN(JAK/ISGF3pathway)SEAPhkb-ifnl
    HEK-Dual™IFN-γHumantypeIIIFN(JAK/STAT-1pathway)SEAP/Luciahkd-ifng
    INTERLEUKINREPORTERCELLS
    HEK293 (human)HEK-Blue™IL-1βHuman&mouseIL-1β(NF-κB/AP-1pathway)SEAPhkb-il1b
    HEK-Blue™IL-1RHuman&mouseIL-1α/β(NF-κB/AP-1pathway)SEAPhkb-il1r
    HEK-Blue™IL-2Human&mouseIL-2(STAT-5pathway)SEAPhkb-il2
    HEK-Blue™CD122/CD132HumanIL-2&IL-15(STAT-5pathway)SEAPhkb-il2bg
    HEK-Blue™IL-4/IL-13HumanIL-4andhuman&mouseIL-13(STAT-6pathway)SEAPhkb-il413
    HEK-Blue™IL-5Human&mouseIL-5(STAT-5pathway)SEAPhkb-il5
    HEK-Blue™IL-6HumanIL-6(STAT-3pathway)SEAPhkb-hil6
    HEK-Blue™IL-7Human&mouseIL-7(STAT-5pathway)SEAPhkb-il7
    HEK-Blue™IL-9Human&mouseIL-9(STAT-5pathway)SEAPhkb-il9
    HEK-Blue™IL-10HumanIL-10(STAT-3pathway)SEAPhkb-hil10
    HEK-Blue™IL-11Human&mouseIL-11(STAT-3pathway)SEAPhkb-il11
    HEK-Blue™IL-12Human&mouseIL-12(STAT-4pathway)SEAPhkb-il12
    HEK-Blue™IL-17HumanIL-17A/Fandhuman&mouseIL-17E(NF-κB/AP-1pathway)SEAPhkb-il17
    HEK-Blue™IL-17CHuman&mouseIL-17C/EandhumanIL-17A(NF-κB/AP-1pathway)SEAPhkb-il17c
    HEK-Blue™IL-18Human&mouseIL-18(NF-κB/AP-1pathway)SEAPhkb-hmil18
    HEK-Blue™IL-22Human&mouseIL-22(STAT-3pathway)SEAPhkb-hmil22
    HEK-Blue™IL-23Human&mouseIL-23(STAT-3pathway)SEAPhkb-hmil23
    HEK-Blue™IL-33HumanIL-33reportercells(NF-κB/AP-1pathway)SEAPhkb-hil33
    HEK-Blue™IL-36HumanIL-36reportercells(NF-κB/AP-1pathway)SEAPhkb-hil36
    TUMORNECROSISFACTORFAMILYCYTOKINES&TUMORGROWTHFACTORREPORTERCELLS
    HEK293 (human)HEK-Blue™CD40LHumanCD40L(NF-κBpathway)SEAPhkb-cd40
    HEK-Blue™RANKLHuman&mouseRANKL(NF-κB/AP-1pathway)SEAPhkb-rankl
    HEK-Blue™TNF-αHuman&mouseTNF-α(NF-κB/AP-1pathway),knockdownofhumanMyD88SEAPhkb-tnfdmyd
    HEK-Dual™TNF-αHuman&mouseTNF-α(NF-κB/AP-1pathway),knockdownofhumanMyD88SEAP/Luciahkd-tnfa
    HEK-Blue™TGF-βHumanTGF-β(TGFBRI/Smad3/4pathway)SEAPhkb-tgfb
    HEK-Blue™TPOHuman&mouseTPO(STAT5pathway)

    CHEMOKINETESTCELLS
    THP-1(human)THP1-Blue™KI-IP10LuciaknockedintohumanIP10(CXCL10)(parentalcelllineTHP1-Blue™NF-κB)SEAP/Luciathpb-ip10kilc


    使用INVIVOGEN细胞因子效应器细胞的优点


    1. 细胞因子生物活性的检测  

    2. 高灵敏度

    3. 成本效益  

    4. 广泛的动态范围

    5. 短暂动手实验

    6. 裸眼视觉化

    7. 适用于药物筛选(普通筛选或高通量筛选,动力学)



    详情请联系 Invivogen 全国授权代理-九游会j9网站首页 


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