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折扣/货期| 货号：36763-1 mg | 规格：1 mg | 目录价：￥616 |
| 货号：36763-10 mg | 规格：10 mg | 目录价：￥4312 |
| 货号：36763-25 mg | 规格：25 mg | 目录价：￥9198 |
| 货号：36763-5 mg | 规格：5 mg | 目录价：￥2464 |
产品详情
产品名称:
WRW4 (trifluoroacetate salt)
别名:
Trp-Arg-Trp-Trp-Trp-Trp-CONH2|Trp-Arg-Trp-Trp-Trp-Trp-NH2|WRWWWW-NH2
产品描述:
WRW4 is a peptide antagonist of formyl peptide receptor 2 (FPR2; IC50 = 0.23 µM) and FPR3, previously known as FPR-like 1 (FPRL1) and FPRL2, respectively.{65277,65278} It inhibits increases in intracellular calcium and chemotaxis induced by the FPR1 and FPR2 agonist WKYMVm (Item No. 33589) in RBL-2H3 cells expressing FPR2 and by the FPR3 agonist F2L in isolated human monocytes when used at a concentration of 10 µM. WRW4 (10 µM) also prevents the production of superoxide induced by amyloid-β (1-42) (Aβ42; Item No. 20574) in isolated human neutrophils.{65277} In vivo, WRW4 (1 mg/kg) increases lung edema and bronchoalveolar lavage fluid (BALF) protein levels in the absence and presence of the antibiotic ceftriaxone (Item No. 18866) in a mouse model of acute lung injury induced by S. pneumoniae.{65279}
保存温度:
-20
运输温度:
-20
预期分子量:
1104.3
产品形式:
A solid
有效期:
1460
纯度:
≥98%
分子式:
C61H65N15O6 • XCF3COOH
上一个:Myelin Basic Protein Peptide (mouse, bovine) (trifluoroacetate salt)
下一个:SOR-C13 (trifluoroacetate salt)
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