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    UTX (human, recombinant)
    品牌:Cayman
    货号:10774 规格:25 µg 目录价:¥5376
    产品详情
    产品名称:
    UTX (human, recombinant)
    别名:
    KDM6A|Ubiquitously Transcribed Tetratricopeptide Repeat X
    产品描述:
    Ubiquitously transcribed tetratricopeptide repeat X (UTX) gene codes for the widely-expressed UTX protein. The UTX gene is localized on the X chromosome and is a homolog of the ubiquitously transcribed mouse Y chromosome (UTY) gene. UTX gene expression has been shown to evade X-chromosome inactivation.{19495} The JmjC-containing UTX protein is a member of the hydroxylase family of enzymes, which are α-ketoglutarate-dependent Fe (II) oxygenases.{19494} UTX plays a crucial role in epigenetic regulation of gene expression by catalyzing the demethylation of tri-methylated lysine 27 on histone H3.{19496} UTX works in opposition to the polycomb repressive complex 2 (PRC2) group protein EZH2, playing a role in cancers with abberant H3K27 methylation.
    保存温度:
    -80
    运输温度:
    -80
    有效期:
    180
    纯度:
    ≥55% estimated by SDS-PAGE
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