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折扣/货期| 货号：36758-1 mg | 规格：1 mg | 目录价：￥3066 |
| 货号：36758-10 mg | 规格：10 mg | 目录价：￥19236 |
| 货号：36758-5 mg | 规格：5 mg | 目录价：￥10430 |
| 货号：36758-500 µg | 规格：500 µg | 目录价：￥1624 |
产品详情
产品名称:
tcY-NH2 (trifluoroacetate salt)
别名:
trans-cinnamoyl-YPGKF-amide|trans-cinnamoyl-YPGKF-NH2|tc-YPGKF-NH2
产品描述:
tcY-NH2 is a synthetic peptide antagonist of proteinase-activated receptor 4 (PAR4) that corresponds to amino acids 1-6 of the amino terminal tethered ligand sequence of mouse PAR4.{36396} It inhibits platelet aggregation induced by the PAR4 agonist AYPGKF-NH2 (Item No. 24258) in washed isolated rat platelets (IC50 = 95-190 µM), as well as induces relaxation of isolated rat aortic rings precontracted with phenylephrine and contraction of isolated rat gastric longitudinal muscle strips (EC50s = 64 and 1 µM, respectively). tcY-NH2 (400 µM) inhibits thrombin-induced migration of primary hepatocellular carcinoma (HCC) cells.{67050} It reduces myocardial infarct size as a percentage of the area at risk ex vivo in a isolated rat heart model of ischemia-reperfusion injury.{67051}
保存温度:
-20
运输温度:
-20
预期分子量:
739.9
产品形式:
A solid
有效期:
1460
纯度:
≥98%
分子式:
C40H49N7O7 • XCF3COOH
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