在病毒感染时,细胞质模式识别受体检测病毒核酸并激活衔接蛋白VISA/ MAVS或MITA/STING介导的先天抗病毒反应。但是关于神经元内分泌功能是否以及如何调节先天抗病毒反应尚不清楚。最近,武汉大学的研究团队在期刊《Cellular & Molecular Immunology》(IF=22.096)上发表题为“β-adrenoreceptor-triggered PKA activation negatively regulates the innate antiviral response.”的文章,该文章研究表明病毒感染降低了β肾上腺素能激素,肾上腺素和去甲肾上腺素的血清水平,以及它们的受体ADRB1和ADRB2。证明肾上腺素/去甲肾上腺素水平的增加以ADRB1-/2依赖的方式抑制了先天性抗病毒反应。机制上,肾上腺素/去甲肾上腺素刺激激活下游激酶PKA,其催化MITA在S241、S243和T263的磷酸化,抑制MITA激活,并抑制对DNA病毒的先天免疫反应。此外,PKA在T54磷酸化VISA拮抗了对RNA病毒的先天免疫反应。这些发现揭示了肾上腺素/去甲肾上腺素的先天性抗病毒反应的调节机制,并为在紧张和焦虑促进的情况下宿主对病毒感染的易感性增加提供了可能的解释。
本文中使用了欣博盛Mouse CXCL10 ELISA kit检测了血清样本中这个细胞因子的含量。
1.文章题目:β-adrenoreceptor-triggered PKA activation negatively regulates the innate antiviral response.
期 刊:Cellular & Molecular Immunology(影响因子:22.096)
发表时间:5 January 2023
作 者:Guo Y, Zhang X N, Su S, et al.
作者单位:武汉大学
使用产品:Mouse CXCL10 ELISA kit
https://pubmed.ncbi.nlm.nih.gov/36600052/
2.文章题目:Dopamine‐Integrated Nanointerface between Fibrillar Matrix and Hydrophilic Nanohydroxyapatite Regulates Immune Microenvironment to Boost Endogenous Bone Regeneration.
期 刊:Advanced Functional Materials(影响因子:19.924)
发表时间:17January 2023
作 者:Li X, Li Z, Wang P, et al.
作者单位:四川大学
使用产品:Mouse IL-1β, TNF-α, IL-4 and IL-10 ELISA kits
https://onlinelibrary.wiley.com/doi/abs/10.1002/adfm.202212738
3.文章题目:Tumor–Antigen Activated Dendritic Cell Membrane-Coated Biomimetic Nanoparticles with Orchestrating Immune Responses Promote Therapeutic Efficacy against Glioma.
期 刊:ACS nano(影响因子:18.027)
发表时间:23 January 2023
作 者:Ma X, Kuang L, Yin Y, et al.
作者单位:重庆大学
使用产品:Mouse TNF-α ELISA kit
https://pubmed.ncbi.nlm.nih.gov/36688797/
4.文章题目:Artificial cilia for soft and stable surface covalent immobilization of bone morphogenetic protein-2.
期 刊:Bioactive Materials(影响因子:16.874)
发表时间:12January 2023
作 者:Gan Q, Chen L, Bei H P, et al.
作者单位:香港理工大学
使用产品:Human BMP-2 ELISA kit
https://pubmed.ncbi.nlm.nih.gov/36714333/
5.文章题目: Inhibition of atherosclerosis progression by modular micelles.
期 刊:Journal of Controlled Release(影响因子:11.467)
发表时间:12 January 2023
作 者:Wang Q, Duan Y, Jing H, et al.
作者单位:上海交通大学
使用产品:Mouse TNF-α ELISA kit
https://pubmed.ncbi.nlm.nih.gov/36638843/
6.文章题目:Dietary genistein increases microbiota-derived short chain fatty acid levels, modulates homeostasis of the aging gut, and extends healthspan and lifespan.
期 刊:Pharmacological Research(影响因子:10.334)
发表时间:21January 2023
作 者:Hou Q, Huang J, Zhao L, et al.
作者单位:中国农业大学
使用产品:Mouse IL-4 ELISA kit
样本类型:结肠组织
https://pubmed.ncbi.nlm.nih.gov/36693599/
7.文章题目:Chemically modified small interfering RNA targeting Hedgehog signaling pathway for rheumatoid arthritis therapy.
期 刊:Molecular Therapy-Nucleic Acids(影响因子:10.183)
发表时间:1January 2023
作 者:Lin L, Zhu S, Huang H, et al.
作者单位:中山大学附属第六医院
使用产品:Mouse TNF-α, IL-1β, and IL-6 ELISA kits
https://pubmed.ncbi.nlm.nih.gov/36618268/
8.文章题目:miR-449a exacerbates acute rejection after liver transplantation via targeting PLOD1 in macrophages.
期 刊:American Journal of Transplantation(影响因子:9.369)
发表时间:12January 2023
作 者:Cao Z R, Zheng W X, Jiang Y X, et al.
作者单位:重庆医科大学
使用产品:Rat IL-1β, IL-6, and TNF-α ELISA kits
https://www.sciencedirect.com/science/article/abs/pii/S1600613522292892
9.文章题目:Type H vessel/platelet‐derived growth factor receptor β+ perivascular cell disintegration is involved in vascular injury and bone loss in radiation‐induced bone damage.
期 刊:Cell Proliferation(影响因子:8.755)
发表时间:24January 2023
作 者:Li J, Chen X, Ren L, et al.
作者单位:中山大学口腔医院
使用产品:Mouse PDGF-BB ELISA kit
https://pubmed.ncbi.nlm.nih.gov/36694343/
10.文章题目:evalsuation the food safety of cultured fat via detection of residues of adipogenic differentiation cocktail in cultured fat with high performance liquid chromatography and enzyme-linked immunosorbent assay.
期 刊:Food Research International(影响因子:7.425)
发表时间:17January 2023
作 者:Song W J, Liu P P, Li C B, et al.
作者单位:南京农业大学
使用产品:Porcine Insulin ELISA kit
https://www.sciencedirect.com/science/article/abs/pii/S0963996923000315
11.文章题目:Salidroside facilitates therapeutic angiogenesis in diabetic hindlimb ischemia by inhibiting ferroptosis.
期 刊:Biomedicine & Pharmacotherapy(影响因子:7.419)
发表时间:12 January 2023
作 者:Wang Y, Han J, Luo L, et al.
作者单位:重庆大学
使用产品:Mouse PDGF-BB and VEGF-A ELISA kits
https://pubmed.ncbi.nlm.nih.gov/36638593/
12.文章题目:An undefined cystatin CsCPI1 from tea plant Camellia sinensis harbors antithrombotic activity.
期 刊:Biomedicine & Pharmacotherapy(影响因子:7.419)
发表时间:25January 2023
作 者:Fang M, Cha J H, Wang H C, et al.
作者单位:广州医科大学
使用产品:Rat CXCL1 ELISA kit
样本类型:脑组织
https://pubmed.ncbi.nlm.nih.gov/36706630/
13.文章题目:Artemisinin exerts a protective effect in the MPTP mouse model of Parkinson's disease by inhibiting microglial activation via the TLR4/Myd88/NF‐KB pathway.
期 刊:CNS Neuroscience & Therapeutics(影响因子:7.035)
发表时间:24 January 2023
作 者:Lv J, Zhu J, Wang P, et al.
作者单位:锦州医科大学
使用产品:Mouse TNF-α and IL-1β ELISA kits
https://pubmed.ncbi.nlm.nih.gov/36691817/
14.文章题目:Extracellular Vesicles Expressing CD19 Antigen Improve Expansion and Efficacy of CD19-Targeted CAR-T Cells.
期 刊:International Journal of Nanomedicine(影响因子:7.033)
发表时间:4 January 2023
作 者:Zhang Y, Ge T, Huang M, et al.
作者单位:华中科技大学
使用产品:Human IFN-γ, TNF-α and IL-2 ELISA kits
https://pubmed.ncbi.nlm.nih.gov/36636644/
15.文章题目:Liujunzi decoction exerts potent antitumor activity in oesophageal squamous cell carcinoma by inhibiting miR-34a/STAT3/IL-6R feedback loop, and modifies antitumor immunity.
期 刊:Phytomedicine(影响因子:6.656)
发表时间:13January 2023
作 者:Han Y, Fan X, Fan L, et al.
作者单位:河南中医药大学
使用产品:Human IL-6Rα ELISA kit
https://pubmed.ncbi.nlm.nih.gov/36701994/
16.文章题目:evalsuation of two laboratory model methods for diarrheal irritable bowel syndrome.
期 刊:Molecular Medicine(影响因子:6.376)
发表时间:12January 2023
作 者:Chen Q, Zhang H, Sun C Y, et al.
作者单位:江西中医药大学
使用产品:Rat IgA ELISA kit
样本类型:结肠组织
https://pubmed.ncbi.nlm.nih.gov/36635623/
17.文章题目:Exploring the mechanism by which aqueous Gynura divaricata inhibits diabetic foot based on network pharmacology, molecular docking and experimental verification.
期 刊:Molecular Medicine(影响因子:6.376)
发表时间:20 January 2023
作 者:Sun Y, Gao C, Liu H, et al.
作者单位:重庆大学
使用产品:Rat IL-6 and TNF-α ELISA kits
https://pubmed.ncbi.nlm.nih.gov/36670362/
18.文章题目:The protective effect of zinc, selenium, and chromium on myocardial fibrosis in the offspring of rats with gestational diabetes mellitus.
期 刊:Food & Function(影响因子:6.317)
发表时间:20 January 2023
作 者:Deng H, Yao X, Cui N, et al.
作者单位:华中科技大学
使用产品:Rat IL-1β, IL-6 and TNF-α ELISA kits
https://pubmed.ncbi.nlm.nih.gov/36661107/
19.文章题目:Aspirin-Loaded Cross-Linked Lipoic Acid Nanodrug Prevents Postoperative Tumor Recurrence by Residual Cancer Cell Killing and Inflammatory Microenvironment Improvement.
期 刊:Bioconjugate Chemistry(影响因子:6.069)
发表时间:10January 2023
作 者:Jing P, Luo Y, Chen Y, et al.
作者单位:四川大学
使用产品:Human TNF-α, IL-6, and IL-10 ELISA kits
https://pubmed.ncbi.nlm.nih.gov/36626242/
20.文章题目:Iron oxide nanoparticles cause surface coating-and core chemistry-dependent endothelial cell ferroptosis.
期 刊:Nanotoxicology(影响因子:5.881)
发表时间:20 January 2023
作 者:Zhang X, Kong F, Wang T, et al.
作者单位:中国医学科学院基础医学研究所
使用产品:Mouse TNF-α ELISA kit
https://pubmed.ncbi.nlm.nih.gov/36660964/
21.文章题目:Streptococcus suis prophage lysin as a new strategy for combating streptococci-induced mastitis and Streptococcus suis infection.
期 刊:Journal of Antimicrobial Chemotherapy(影响因子:5.758)
发表时间:20 January 2023
作 者:Li X X, Zhang F Q, Wang S, et al.
作者单位:华中农业大学
使用产品:Mouse TNF-α ELISA kits
https://pubmed.ncbi.nlm.nih.gov/36659862/
22.文章题目:Hyperoside attenuates Cd-induced kidney injury via inhibiting NLRP3 inflammasome activation and ROS/MAPK/NF-κB signaling pathway in vivo and in vitro.
期 刊:Food and Chemical Toxicology(影响因子:5.572)
发表时间:5 January 2023
作 者:Li Z, Liao W, Yin X, et al.
作者单位:南方医科大学
使用产品:Mouse IL-1β, IL-18 and Human IL-1β, IL-6, IL-18 ELISA kits
https://pubmed.ncbi.nlm.nih.gov/36610472/
23.文章题目:Purification, Characterization and Bioactivity of Different Molecular-Weight Fractions of Polysaccharide Extracted from Litchi Pulp.
期 刊:Foods(影响因子:5.561)
发表时间:1January 2023
作 者:Zou X, Cai J, Xiao J, et al.
作者单位:广东省农业科学院
使用产品:Mouse IL-6 and TNF-α ELISA kits
https://pubmed.ncbi.nlm.nih.gov/36613408/
24.文章题目:E2F1-deficient adipose-derived stem cells improve skin wound closure in mice by upregulating paracrine expression of VEGF and TGF-β1.
期 刊:Plastic and Reconstructive Surgery(影响因子:5.169)
发表时间:3January 2023
作 者:Yi Z, Wu Y, Zhang Q, et al.
作者单位:华中科技大学
使用产品:Mouse VEGF and TGF-β1 ELISA kits
https://journals.lww.com/plasreconsurg/Abstract/9900/E2F1__deficient_adipose_derived_stem_cells_improve.1465.aspx
25.文章题目:Targeting Noncanonical Pyroptosis With a Small Molecular Inhibitor Alleviates Inflammation in the LPS-Induced Keratitis Mouse Model.
期 刊:Investigative Ophthalmology & Visual Science(影响因子:4.925)
发表时间:3January 2023
作 者:Zhang Y, Zhou N, Jiao Y, et al.
作者单位:四川大学华西医院
使用产品:Human IL-1β ELISA kit
https://pubmed.ncbi.nlm.nih.gov/36595275/
26.文章题目:The Antiangiogenic and Antitumor Effects of Scoparasin B in Non-Small-Cell Lung Cancer.
期 刊:Journal of Natural Products(影响因子:4.803)
发表时间:24January 2023
作 者:Lin K, Huang L, Zhang Y, et al.
作者单位:广州医科大学
使用产品:Human VEGF ELISA kit
https://pubmed.ncbi.nlm.nih.gov/36692021/
27.文章题目:Canagliflozin Pretreatment Attenuates Myocardial Dysfunction and Improves Postcardiac Arrest Outcomes After Cardiac Arrest and Cardiopulmonary Resuscitation in Mice.
期 刊:Cardiovascular Drugs and Therapy(影响因子:3.947)
发表时间:7January 2023
作 者:Ju F, Abbott G W, Li J, et al.
作者单位:四川大学华西医院
使用产品:Mouse IL-6 and TNF-α ELISA kits
https://pubmed.ncbi.nlm.nih.gov/36609949/
28.文章题目:Stanniocalcin-1 secreted by human umbilical mesenchymal stem cells regulates interleukin-10 expression via the PI3K/AKT/mTOR pathway in alveolar macrophages.
期 刊:Cytokine(影响因子:3.926)
发表时间:3January 2023
作 者:Xia T T, Hu R, Shao C J, et al.
作者单位:锦州医科大学
使用产品:Human IL-10 ELISA kit
https://pubmed.ncbi.nlm.nih.gov/36603482/
29.文章题目:Yishen Xiezhuo formula ameliorates the development of cisplatin-induced acute kidney injury by attenuating renal tubular epithelial cell senescence.
期 刊:Annals of Translational Medicine(影响因子:3.616)
发表时间:1January 2023
作 者:Zhang Q, Qi J, Luo Q, et al.
作者单位:南方医科大学
使用产品:Human IL-6 and IL-1β ELISA kits
https://pubmed.ncbi.nlm.nih.gov/36660714/
30.文章题目:Resveratrol-Loaded Dipalmitoylphosphatidylcholine Liposomal Large Porous Microparticle Inhalations for the Treatment of Bacterial Pneumonia Caused by Acinetobacter baumannii.
期 刊:Journal of Aerosol Medicine and Pulmonary Drug Delivery(影响因子:3.44)
发表时间:24January 2023
作 者:Yu Z, Wu T, Liu X, et al.
作者单位:同济大学医学院
使用产品:Mouse TNF-α and IL-1β ELISA kits
https://pubmed.ncbi.nlm.nih.gov/36695669/
31.文章题目:Trilobatin Ameliorates Inflammatory Response by Regulating the miR375-Mediated Fatty Acid Binding Protein 4 Expression in Adipocytes.
期 刊:Revista Brasileira de Farmacognosia(影响因子:2.464)
发表时间:4January 2023
作 者:Li X, Wu Y, Jiang X, et al.
作者单位:重庆理工大学
使用产品:Mouse TNF-α and IL-6 ELISA kits
https://link.springer.com/article/10.1007/s43450-022-00356-5
32.文章题目:Knockdown of TRIM8 alleviates dextran sulfate sodium-induced colitis in mice by inhibiting the NF-κB signaling pathway.
期 刊:Allergologia et Immunopathologia,(影响因子:2.094)
发表时间:1 January 2023
作 者:Qiu T, Lv Y, Niu L, et al.
作者单位:陕西省人民医院
使用产品:Mouse IL-1β, IL-6 and TNF-α ELISA kits
样本类型:结肠组织
https://pubmed.ncbi.nlm.nih.gov/36617827/
33.文章题目:Exposure to particulate matter 2.5 leading to lung microbiome disorder and the alleviation effect of Auricularia auricular-judae polysaccharide.
期 刊:International Journal of Occupational Medicine and Environmental Health(影响因子:1.828)
发表时间:1January 2023
作 者:Zhang Y, He B, Wu L, et al.
作者单位:华北理工大学
使用产品:Rat IFN-γ, IL-4, IL-8 and IL-10 ELISA kits
样本类型:肺组织
https://pubmed.ncbi.nlm.nih.gov/35913271/
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