货号:30430 | 规格:1 mg | 目录价:¥18662 |
产品详情
产品名称:
SARS-CoV-2 Spike Glycoprotein (433-506)
别名:
SARS-CoV-2 Surface Glycoprotein|Severe Acute Respiratory Syndrome Coronavirus 2 Spike Glycoprotein
产品描述:
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike glycoprotein (433-506) is a fragment of the SARS-CoV-2 spike glycoprotein, also known as the surface glycoprotein, encoded by the S gene in SARS-CoV-2 RNA.{53462} It contains amino acids 433-506 of the full-length SARS-CoV-2 spike glycoprotein sequence. SARS-CoV-2 is an enveloped positive-stranded RNA virus, a member of the Betacoronavirus genus, and the causative agent of COVID-19.{53462,53459,53461,55257,55258} The SARS-CoV-2 spike glycoprotein is located on the outer envelope of the virion.{53462} It is composed of an S1 and S2 subunit divided by a furin S-cleavage site not found in other SARS-CoVs.{46767,49561} The S1 subunit contains the receptor-binding domain (RBD), which binds to the carboxypeptidase angiotensin-converting enzyme 2 (ACE2), and the S1 and S2 subunits are cleaved by the protease TMPRSS2 to facilitate viral fusion with the host cell membrane.{49542,49536,49558} Cayman’s SARS-CoV-2 Spike Glycoprotein (433-506) contains the SARS-CoV-2 receptor binding motif (Item No. 30428) and a disulfide bridge between Cys480 and Cys488.
保存温度:
-80
运输温度:
-80
有效期:
365
纯度:
≥95%
上一个:SARS-CoV-2 Spike Glycoprotein Receptor Binding Domain (human IgG1 Fc-tagged)
下一个:SARS-CoV-2 Spike Glycoprotein Receptor Binding Domain (rabbit IgG1 Fc-tagged)
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