Recombinant Rat IL-21-细胞因子、趋化因子与生长因子-ELISA_抗体_蛋白_核苷酸

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Recombinant Rat IL-21

品牌：PeproTech

官网链接

说明书

折扣/货期

货号：400-41-100ug	规格：100ug	目录价：￥22246
货号：400-41-10ug	规格：10ug	目录价：￥2850
货号：400-41-1mg	规格：1mg	目录价：￥89085
货号：400-41-250ug	规格：250ug	目录价：￥38900
货号：400-41-2ug	规格：2ug	目录价：￥1169
货号：400-41-500ug	规格：500ug	目录价：￥57794

产品详情

产品名称:

Recombinant Rat IL-21

别名:

Interleukin-21

产品描述:

IL‐21 is a pleiotropic cytokine produced by CD4+ T cells in response to antigenic stimulation. Its action generally enhances antigen‐specific responses of immune cells. The biological effects of IL‐21 include: inducing the differentiation of T cell‐stimulated B cells into plasma cells and memory B cells; the stimulation of IgG production in conjunction with IL‐4; and the induction of apoptotic effects in naïve B cells and stimulated B cells in the absence of T cell signaling. Additionally, IL‐21 promotes the anti‐tumor activity of CD8+ T cells and NK cells. IL‐21 exerts its effect through binding to a specific type I cytokine receptor, IL‐21R, which also contains the γ chain (γc) found in other cytokine receptors, including IL‐2, IL‐4, IL‐7, IL‐9 and IL‐15. The IL‐21/IL‐21R interaction triggers a cascade of events, which includes activation of the tyrosine kinases JAK1 and JAK3, followed by activation of the transcription factors STAT1 and STAT3. Recombinant Rat IL‐21 is a 15.3 kDa protein containing 130 amino acid residues.

宿主来源:

E.coli

推荐稀释度:

请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度

预期分子量:

15.3 kDa

产品形式:

Bulk

产地:

美国

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