货号:120-17-100ug | 规格:100ug | 目录价:¥22138 |
货号:120-17-10ug | 规格:10ug | 目录价:¥2836 |
货号:120-17-1mg | 规格:1mg | 目录价:¥88652 |
货号:120-17-250ug | 规格:250ug | 目录价:¥38710 |
货号:120-17-2ug | 规格:2ug | 目录价:¥1163 |
货号:120-17-500ug | 规格:500ug | 目录价:¥57513 |
货号:120-17-50ug | 规格:50ug | 目录价:¥13268 |
产品详情
产品名称:
Recombinant Human Wnt-1
别名:
INT-1, Wnt-1 proto-oncogene protein (precursor)
产品描述:
Wnt-1 is a secreted protein that signals through the Frizzled family of cell surface receptors, and is required for normal embryonic development. Wnt-1 activation induces a complex signaling cascade that ultimately leads to the increased expression of over fifty genes. An important component of Wnt-1 signaling is the stabilization, and resulting accumulation, of the intracellular signaling protein, beta-catenin. Wnt signaling induces and maintains the transformed phenotype, and, in certain embryonic cell lines, supports self-renewal in the absence of significant differentiation. Elevated levels of Wnt proteins are associated with tumorigenesis, and are present in numerous human breast cancers. Mature human Wnt-1 is a glycosylated protein containing 343 amino acid residues. Recombinant Human Wnt-1 is a 38.4 kDa, non-glycosylated protein containing 343 amino acid residues.
宿主来源:
E.coli
推荐稀释度:
请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度
预期分子量:
38.4 kDa
产品形式:
Bulk
产地:
美国
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