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折扣/货期| 货号：100-35-100ug | 规格：100ug | 目录价：￥22246 |
| 货号：100-35-10ug | 规格：10ug | 目录价：￥2850 |
| 货号：100-35-1mg | 规格：1mg | 目录价：￥89085 |
| 货号：100-35-250ug | 规格：250ug | 目录价：￥38900 |
| 货号：100-35-2ug | 规格：2ug | 目录价：￥1169 |
| 货号：100-35-500ug | 规格：500ug | 目录价：￥57794 |
产品详情
产品名称:
Recombinant Human TGF-beta2 (Insect derived)
别名:
Transforming Growth Factor-beta2, Glioblastoma-derived T cell suppressor factor, BSC-1, Cetermin, Polyergin
产品描述:
The three mammalian isoforms of TGF-beta, TGF-beta1, beta2, and beta3, signal through the same receptor and elicit similar biological responses. They are multifunctional cytokines that regulate cell proliferation, growth, differentiation and motility, as well as synthesis and deposition of the extracellular matrix. They are involved in various physiological processes, including embryogenesis, tissue remodeling and wound healing. They are secreted predominantly as latent complexes, which are stored at the cell surface and in the extracellular matrix. The release of the biologically active TGF-beta isoform from a latent complex involves proteolytic processing of the complex and/or induction of conformational changes by proteins such as thrombospondin-1. TGF-beta2 has been shown to exert suppressive effects on IL-2-dependent T-cell growth, and may also have an autocrine function in enhancing tumor growth by suppressing immunosurveillance of tumor development. Recombinant Human TGF-beta2 is a 25.0 kDa protein composed of two identical 112 amino acid polypeptide chains linked by a single disulfide bond.
宿主来源:
(BTI-Tn-5B1-4) Hi-5 Insect cells
推荐稀释度:
请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度
预期分子量:
25 kDa
产品形式:
Bulk
产地:
美国
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