货号:120-35-100ug | 规格:100ug | 目录价:¥5760 |
货号:120-35-10ug | 规格:10ug | 目录价:¥1163 |
货号:120-35-1mg | 规格:1mg | 目录价:¥25574 |
货号:120-35-250ug | 规格:250ug | 目录价:¥11161 |
货号:120-35-500ug | 规格:500ug | 目录价:¥16583 |
货号:120-35-50ug | 规格:50ug | 目录价:¥2900 |
产品详情
产品名称:
Recombinant Human Osteopontin
别名:
Bone sialoprotein 1, Secreted phosphoprotein 1, SPP-1, Nephropontin, Uropontin
产品描述:
Osteopontin is a secreted glycoprotein that functions as a ligand to alphavbeta3 integrin and possibly other receptors. It binds tightly to hydroxyapatite and can act as a structural component of the extracellular mineralized matrix. Osteopontin is initially secreted as a 298 amino acid protein, which is subject to multiple post-translational modifications including glycosylation, phosphorylation, and specific proteolytic cleavages into various smaller molecular weight fragments. Osteopontin is expressed in a wide range of cells and tissues including osteoblasts, various tumor cell lines, extraosseous cells in the inner ear, brain, kidney, deciduum, placenta and odontoblasts. In addition to its involvement in mineralized matrix formation, Osteopontin can also function as a cytokine that stimulates the release of IFNgamma and IL-12, while inhibiting the production of IL-10. Recombinant human Osteopontin is a 298 amino acid protein, which, due to glycosylation, migrates at an apparent molecular weight of 60.0-65.0 kDa by SDS-PAGE analysis under reducing conditions.
宿主来源:
HEK293 cells
推荐稀释度:
请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度
预期分子量:
33.7 kDa
产品形式:
Bulk
产地:
美国
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