货号:420-01-100ug | 规格:100ug | 目录价:¥22138 |
货号:420-01-10ug | 规格:10ug | 目录价:¥2836 |
货号:420-01-1mg | 规格:1mg | 目录价:¥88652 |
货号:420-01-250ug | 规格:250ug | 目录价:¥38710 |
货号:420-01-2ug | 规格:2ug | 目录价:¥1163 |
货号:420-01-500ug | 规格:500ug | 目录价:¥57513 |
货号:420-01-50ug | 规格:50ug | 目录价:¥13268 |
产品详情
产品名称:
Recombinant Human MMP-1
别名:
Matrix Metalloproteinase-1, Fibroblast Collagenase, Interstitial Collagenase
产品描述:
Matrix metalloproteinases (MMPs) are a family of endoproteases that require zinc and calcium for expressing catalytic activity. These enzymes play a central role in the maintenance and remodeling of the extracellular matrix. Elevated expression of their activity, caused either by up-regulation of their expression or down-regulation of their cognate inhibitors, has been implicated in various degenerative disorders, including arthritis, cardiovascular disease, skeletal growth-plate disorders, and cancer metastasis. MMP-1 is a secreted collagenase with specificity toward Type I, II, III, VII, and X collagens. Recombinant Human MMP-1 is a 42.7 kDa protein containing the entire catalytic N-terminal domain and the C-terminal domain, which is involved in substrate specificity, and in binding TIMP-1.
宿主来源:
E.coli
推荐稀释度:
请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度
预期分子量:
42.7 kDa
产品形式:
Bulk
产地:
美国
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