货号:450-06-100ug | 规格:100ug | 目录价:¥11600 |
货号:450-06-1mg | 规格:1mg | 目录价:¥51397 |
货号:450-06-250ug | 规格:250ug | 目录价:¥22431 |
货号:450-06-25ug | 规格:25ug | 目录价:¥2910 |
货号:450-06-500ug | 规格:500ug | 目录价:¥33338 |
货号:450-06-5ug | 规格:5ug | 目录价:¥1169 |
产品详情
产品名称:
Recombinant Human MANF
别名:
Mesencephalic Astrocyte-derived Neurotrophic Factor, ARMET, Arginine-rich protein (ARP)
产品描述:
MANF is a secreted neurotrophic factor that is expressed in brain, neuronal and certain non-neuronal tissues. It has been shown to promote the survival, growth and function of dopamine-specific neurons. MANF and its structural homolog CDNF each contain a N-terminal, saposin-like, lipid-binding domain, and a carboxyl-terminal domain that is not homologous to previously characterized protein structures. MANF and CDNF can prevent 6-OHDA-induced degeneration of dopaminergic neurons by triggering survival pathways in a rat experimental model of Parkinson's disease. Recombinant Human MANF is an 18.1 kDa protein consisting of 158 amino acids, including 8 cysteine residues.
宿主来源:
E.coli
推荐稀释度:
请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度
预期分子量:
18.1 kDa
产品形式:
Bulk
产地:
美国
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