货号:100-39H-100ug | 规格:100ug | 目录价:¥11550 |
货号:100-39H-1mg | 规格:1mg | 目录价:¥51148 |
货号:100-39H-250ug | 规格:250ug | 目录价:¥22322 |
货号:100-39H-25ug | 规格:25ug | 目录价:¥2900 |
货号:100-39H-500ug | 规格:500ug | 目录价:¥33176 |
货号:100-39H-5ug | 规格:5ug | 目录价:¥1163 |
产品详情
产品名称:
Recombinant Human HGF (HEK293 derived)
别名:
Hepatocyte Growth Factor, Scatter Factor (SF), Hepatopoietin (HPTA)
产品描述:
HGF is a potent, mesenchymally-derived mitogen for mature parenchymal hepatocytes, and acts as a growth factor for a broad spectrum of tissues and cell types. HGF signals through a transmembrane tyrosine kinase receptor known as MET. Activities of HGF include the induction of cell proliferation, motility, morphogenesis, inhibition of cell growth, and enhancement of neuron survival. HGF is a crucial mitogen for liver regeneration processes, especially after partial hepatectomy and other liver injuries. Human and murine HGF are cross-reactive. Human HGF is expressed as a linear, polypeptide-precursor glycoprotein containing 697 amino acid residues. Proteolytic processing of this precursor generates the biologically active heterodimeric form of HGF, which consists of two polypeptide chains (alpha-chain and beta-chain) held together by a single disulfide bond resulting in formation of a biologically active heterodimer. The alpha-chain consists of 463 amino acid residues and four kringle domains. The beta-chain consists of 234 amino acid residues. Recombinant Human HGF, sourced from HEK293 cells, is a 79.4 kDa polypeptide consisting of 695 amino acid residues. As a result of glycosylation, Recombinant Human HGF migrates with an apparent molecular mass of approximately 68-85 kDa by SDS-PAGE gel, under non-reducing conditions.
宿主来源:
HEK293 cells
推荐稀释度:
请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度
预期分子量:
79.4 kDa
产品形式:
Bulk
产地:
美国
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