官网链接
折扣/货期| 货号：160-03-100ug | 规格：100ug | 目录价：￥5790 |
| 货号：160-03-10ug | 规格：10ug | 目录价：￥1169 |
| 货号：160-03-1mg | 规格：1mg | 目录价：￥25699 |
| 货号：160-03-250ug | 规格：250ug | 目录价：￥11215 |
| 货号：160-03-500ug | 规格：500ug | 目录价：￥16664 |
| 货号：160-03-50ug | 规格：50ug | 目录价：￥2910 |
产品详情
产品名称:
Recombinant Human FGFR2a (IIIc) Fc
别名:
Fibroblast Growth Factor Receptor 2 alpha, BEK, KGFR
产品描述:
The FGF family plays a central role during prenatal development and postnatal growth, and the regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. The FGF ligands bind to a family of type I transmembrane tyrosine kinase receptors, which leads to dimerization and activation by sequential autophosphorylation of specific tyrosine residues. Four genes encoding structurally related FGF receptors (FGFR-1 to -4) are known. Alternative splicing of the mRNAs generates numerous forms of FGFR-1 to -3. Alternate forms of FGF receptors can exhibit different specificities with respect to ligand binding. For example, the form designated as FGFR1a (IIc) interacts predominantly with FGF-acidic (FGF1) and FGF-basic (FGF2). A frequent splicing event involving FGFR-1 and -2 results in receptors containing all three Ig domains, referred to as the alpha isoform, or only IgII and IgIII, referred to as thebeta isoform. Only the alpha isoform has been identified for FGFR-3 and FGFR-4. Additional splicing events for FGFR-1 to -3, involving the C-terminal half of the IgIII domain encoded by two mutually exclusive alternative exons, generate FGF receptors with alternative IgIII domains (IIIb and IIIc). Recombinant Human FGFR2a (IIIc) is a 65.6 kDa protein containing 589 amino acids. Under reducing conditions, FGFR2a migrates between 100-110 kDa on SDS-PAGE gel.
宿主来源:
CHO cells
推荐稀释度:
请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度
预期分子量:
65.6 kDa
产品形式:
Bulk
产地:
美国
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