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折扣/货期| 货号：120-40-100ug | 规格：100ug | 目录价：￥16674 |
| 货号：120-40-10ug | 规格：10ug | 目录价：￥2850 |
| 货号：120-40-1mg | 规格：1mg | 目录价：￥66806 |
| 货号：120-40-250ug | 规格：250ug | 目录价：￥29185 |
| 货号：120-40-2ug | 规格：2ug | 目录价：￥1169 |
| 货号：120-40-500ug | 规格：500ug | 目录价：￥43351 |
产品详情
产品名称:
Recombinant Human BMP-10
别名:
Bone Morphogenetic Protein-10
产品描述:
Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-beta superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body and are involved in diverse physiological processes during both pre- and postnatal life. BMP-10 plays a crucial role in the development of the embryonic heart by acting to stimulate and maintain cardiomyocyte proliferation. It can signal through various receptor complexes usually containing BMPR-1A, BMPR-1B, ALK1, ALK3, or ALK6. The interaction of BMP-10 with its specific receptors can induce signaling initiated by the phosphorylation of SMAD transcription factors, including SMAD1, SMAD5, or SMAD8, but can also induce SMAD independent processes. BMP-10 is structurally related to BMP-9, and both can inhibit endothelial cell proliferation and migration. Recombinant Human BMP-10 is a 24.4 kDa homodimeric disulfide-linked protein consisting of two 108 amino acid subunits, which correspond to amino acid residues 317 to 424 of the full-length BMP-10 precursor.
宿主来源:
HEK293 cells
推荐稀释度:
请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度
预期分子量:
24.4 kDa
产品形式:
Bulk
产地:
美国
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