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Nucleosome, Recombinant Human, H3K14ub1 dNuc, Biotinylated
品牌：EpiCypher
货号：16-0398 规格：25 µg 目录价：￥6300
产品详情
产品名称:
Nucleosome, Recombinant Human, H3K14ub1 dNuc, Biotinylated
产品描述:
H3K14ub1 designer mononucleosomes (dNucs) consist of 147 base pairs of DNA wrapped around an octamer core of histone proteins (two each of H2A, H2B, H3.1 and H4) to form a nucleosome, the basic repeating unit of chromatin. H3K14ub1 has been shown to promote the activity of the methyltransferase Clr4, which methylates H3K9, a known repressive mark [1]. The 147 bp 601 sequence, identified by Lowary & Widom [2], has high affinity for histone octamers and is useful for nucleosome assembly. The DNA in this nucleosome contains a 5’ biotin-TEG group. H3K14ub1 has a Cys to Ala substitution at position 110.
宿主来源:
Human
表达系统:
E. coli & synthetic DNA
保存温度:
Stable for six months at -80°C from date of receipt. For best results, aliquot and avoid freeze/thaws.
运输温度:
Dry ice.
产品形式:
1.115 mg/mL mononucleosome in 22.6 µL 10 mM Tris HCl pH 7.5, 25 mM NaCl, 1 mM EDTA, 2 mM DTT, 20% glycerol. (14.4 µg protein, 25 µg DNA + protein)
产地:
美国
生产商:
EpiCypher
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