货号:35310-1 mg | 规格:1 mg | 目录价:¥560 |
货号:35310-10 mg | 规格:10 mg | 目录价:¥4410 |
货号:35310-25 mg | 规格:25 mg | 目录价:¥9646 |
货号:35310-5 mg | 规格:5 mg | 目录价:¥2492 |
产品详情
产品名称:
Nogo-66 (1-40) (human, mouse, rat) (trifluoroacetate salt)
别名:
NEP1-40|Nogo-40|Nogo-A Inhibitory Peptide|RIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNS-NH2
产品描述:
Nogo-66 (1-40) is a peptide fragment of Nogo-A that corresponds to the extracellular domain, Nogo-66, which can induce neurite growth cone collapse in oligodendrocytes.{66166,66167} It is also an antagonist of the Nogo-66 receptor (NgR).{66167} It inhibits binding of the NgR agonist AP-Nogo-66 to, and inhibits growth cone collapse induced by the NgR agonist GST-Nogo-66 in, embryonic day 12 (E12) chick dorsal root ganglia (DRG) explants.{66167} Nogo-66 (1-40) partially reverses axonal outgrowth inhibition induced by purified CNS myelin in E12 chick DRG explants (EC50 = 50 nM). It also induces regeneration of corticospinal tract fibers and improves locomotor function in a rat model of midthoracic spinal cord hemisection injury when administered intrathecally at a dose of 75 µg/kg per day.
保存温度:
-20
运输温度:
-20
预期分子量:
4739.1
产品形式:
A solid
有效期:
1460
纯度:
≥95%
分子式:
C206H324N56O65 • CF3COOH
上一个:Bradykinin Fragment (1-5) (trifluoroacetate salt)
下一个:Hemokinin 1 (human) (trifluoroacetate salt)
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