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折扣/货期| 货号：SKT-126-480 | 规格：96 well x5 | 目录价：￥25177.5 |
产品详情
产品名称:
Nitrotyrosine ELISA Kit
别名:
Nitro tyrosine ELISA Kit, 3-Nitrotyrosine ELISA Kit, 3-Nitro-L-tyrosine ELISA Kit, 3 Nitrotyrosine ELISA Kit, 3-NT ELISA Kit, 3NT ELISA Kit
产品描述:
Colorimetric detection of Nitrotyrosine
反应种属:
Species Independent
保存温度:
4ºC and -20ºC
运输温度:
Blue Ice
产地:
加拿大
功能与背景:
Nitrotyrosine has been identified as a marker of inflammation and NO production. Nitrotyrosine is formed in presence of the active metabolite NO. Various pathways including the formation of peroxinitrite lead to nitrotyrosine production. Since nitrotyrosine is a stable end product of peroxynitrite oxidation, assessment of its plasma concentration may be useful as a marker of NO-dependent damage in vivo. Since NOX is only an indicator for enhanced NO production, protein associated nitrotyrosine might be a more suitable marker for damage induced by reactive nitrogen intermediates derived from NO. Furthermore, most proteins have a longer half life in the circulation than NOX levels. The presence of nitrotyrosine has been detected in various inflammatory processes including atherosclerotic plaques, celiac disease, rheumatoid arthritis, chronic renal failure and septic shock. In normal plasma low, undetectable, levels of nitrotyrosine are present.
Nitrosylation of the amino acid tyrosine occurs both for free tyrosine and for protein bound tyrosine.
灵敏度:
50 nM
检测范围:
62.5 - 8000 nM
检测方法:
Competitive
样本类型:
Plasma | Serum | Cell Lysates | Urine
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