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Nitrotyrosine Affinity Sorbent
品牌:Cayman
货号:389549 规格:200 µg 目录价:¥4200
产品详情
产品名称:
Nitrotyrosine Affinity Sorbent
别名:
3-Nitrotyrosine|NT
产品描述:
Nitrotyrosine is a post-translational modification that is formed by the nitration of tyrosine.{60009} It exists in a free or protein-bound form and is commonly used as a marker of nitrosative or oxidative stress.{31710} Nitrotyrosine residues have been found in a variety of proteins, including LDL, surfactant protein A, angiotensin II, and human and bovine serum albumin.{60010} Nitrotyrosine levels are increased in the affected tissues of numerous pathological conditions, including atherosclerosis, cancer, ulcerative colitis, Alzheimer's disease, and Parkinson's disease.{60010} Autoantibodies that recognize nitrotyrosinated proteins are increased in the synovium of patients with rheumatoid arthritis and are positively correlated with joint and tendon inflammation.{60009} Cayman's Nitrotyrosine Affinity Sorbent is designed for immunoprecipitation (IP) of nitrated proteins from biological samples. The nitrotyrosine affinity sorbent consists of Cayman's Nitrotyrosine Monoclonal Antibody (Item No. 189542) coupled to protein A agarose. This is an effective way to concentrate nitrated proteins for subsequent detection by a different anti-nitrotyrosine antibody by Western blot (WB).
实验应用:
IP, WB
保存温度:
4
运输温度:
4
产品形式:
200 µg of anti-Nitrotyrosine Monoclonal Antibody (Item No. 189542) coupled to protein A agarose; supplied as a 50% slurry in PBS, pH 7.2, with 0.02% sodium azide
有效期:
365
来源:
Animal/Mouse
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