• 九游会j9网站首页,j9九游会首页登录,j9九游会ag真人官网

    您好,欢迎光临九游会j9网站首页商城!
    服务热线:400 680 0892
    新闻资讯 News

    BioXcell热销产品--InVivoPlus anti-mouse CD8α

    2023-04-27
    浏览次数: 61

    BioXcell热销产品--InVivoPlus anti-mouse CD8α

     

    产品描述:

    BioXcell InVivoPlus anti-mouse CD8α克隆号YTS 169.4单克隆抗体能与小鼠CD8α反应。CD8抗原是一种跨膜糖蛋白,作为T细胞受体的共受体。与TCR一样,CD8与抗原呈递细胞(APC)展示的I类MHC分子结合。CD8主要在细胞毒性T细胞表面表达,但也可在胸腺细胞、自然杀伤细胞和一些树突状细胞亚群中发现。CD8最常见的存在形式是由一个CD8α和一个CD8β链组成的异二聚体,然而,它也可以是由两个CD8α链组成的同二聚体。CD8α和CD8β链均与免疫球蛋白可变轻链具有显著同源性。每个CD8链的分子量约为34 kDa。BioXcell InVivoPlus anti-mouse CD8α克隆号YTS 169.4抗体在体内使用时显示出depleting活性。


    BioXcell热销产品--InVivoPlus anti-mouse CD8α 

    产品详情:


    产品名称

    InVivoPlus anti-mouse CD8α

    产品货号

    BP0117

    产品规格

    5/25/50/100mg

    反应种属

    Mouse

    克隆号

    YTS 169.4

    同种型

    Rat IgG2b, κ

    免疫原

    CBA mouse thymocytes

    实验应用

    in vivo CD8+ T cell depletion
    Western blot

    产品形式

    PBS, pH 7.0,Contains no stabilizers or preservatives

    纯度

    >95%, Determined by SDS-PAGE

    聚合

    <5%, Determined by SEC

    无菌处理

    0.2 µm filtration

    纯化方式

    Protein G

    RRID

    AB_10950145

    分子量

    150 kDa

    小鼠病原检测

    Ectromelia/Mousepox Virus: Negative

    Hantavirus: Negative

    K Virus: Negative

    Lactate Dehydrogenase-Elevating Virus: Negative

    Lymphocytic Choriomeningitis virus: Negative

    Mouse Adenovirus: Negative

    Mouse Cytomegalovirus: Negative

    Mouse Hepatitis Virus: Negative

    Mouse Minute Virus: Negative

    Mouse Norovirus: Negative

    Mouse Parvovirus: Negative

    Mouse Rotavirus: Negative

    Mycoplasma Pulmonis: Negative

    Pneumonia Virus of Mice: Negative

    Polyoma Virus: Negative

    Reovirus Screen: Negative

    Sendai Virus: Negative

    Theiler’s Murine Encephalomyelitis: Negative

    保存条件

    抗体原液保存在4°C,不能冷冻保存。

    推荐同型对照

    InVivoPlus rat IgG2b isotype control, anti-keyhole limpet hemocyanin(货号BP0090)

    推荐抗体稀释液

    InVivoPure pH 7.0 Dilution Buffer(货号IP0070)



    为什么选择InVivoPlus抗体?

    InVivoPlus级别的产品内毒素含量更低,经过多种实验验证,更适合用于体内实验研究

    BioXcell热销产品--InVivoPlus anti-mouse CD8α


     该产品自上市已被多篇SCI文献引用,品质有保证,以下是部分已发表的文献引用:


    应用

    文章

    体内CD8+T细胞耗竭

    (in vivo CD8+ T cell depletion)

    1. Vashist, N., et al. (2018). 'Influenza-Activated ILC1s Contribute to Antiviral Immunity Partially Influenced by Differential GITR Expression' Front Immunol 9: 505.

    2. Triplett, T. A., et al. (2018). 'Reversal of indoleamine 2,3-dioxygenase-mediated cancer immune suppression by systemic kynurenine depletion with a therapeutic enzyme' Nat Biotechnol 36(8): 758-764.

    3. Carmi, Y., et al. (2015). 'Allogeneic IgG combined with dendritic cell stimuli induce antitumour T-cell immunity' Nature 521(7550): 99-104.

    4. Burrack, K. S., et al. (2015). 'Myeloid Cell Arg1 Inhibits Control of Arthritogenic Alphavirus Infection by Suppressing Antiviral T Cells' PLoS Pathog 11(10): e1005191.

    5. Wensveen, F. M., et al. (2015). 'NK cells link obesity-induced adipose stress to inflammation and insulin resistance' Nat Immunol 16(4): 376-385.

    6. Li, Z., et al. (2015). 'Pre-treatment of allogeneic bone marrow recipients with the CXCR4 antagonist AMD3100 transiently enhances hematopoietic chimerism without promoting donor-specific skin allograft tolerance' Transpl Immunol 33(2): 125-129.

     

     

    BioXcell热销产品--InVivoPlus anti-mouse CD8α

    更多产品详情请咨询 BioXcell 中国授权代理——欣博盛生物

    全国服务热线: 4006-800-892       邮箱: market@qckc0531.com 

    深圳: 0755-26755892         北京: 010-88594029            

    广州:020-87615159           上海: 021-34613729

    代理品牌网站: www.qckc0531.com 

    自主品牌网站: www.neobiosescience.net

    分享到:
    关注欣博盛公众号
    Copyright ©2021 - 2023 深圳九游会j9网站首页有限公司
      网站地图
    犀牛云提供企业云服务
    九游会j9网站首页