货号:36964-1 mg | 规格:1 mg | 目录价:¥406 |
货号:36964-10 mg | 规格:10 mg | 目录价:¥3150 |
货号:36964-25 mg | 规格:25 mg | 目录价:¥6888 |
货号:36964-5 mg | 规格:5 mg | 目录价:¥1792 |
产品详情
产品名称:
Myelin Basic Protein Peptide Antagonist (trifluoroacetate salt)
别名:
EKPKVEAYKAAAAPA-OH|MBP Peptide Antagonist
产品描述:
Myelin basic protein (MBP) peptide antagonist is a synthetic peptide antagonist against the multiple sclerosis (MS) autoantigen MBP.{64665} MBP peptide antagonist binds to the immunomodulatory region of MBP, corresponding to residues 85-99 and inhibits MBP binding to human HLA-DR2 in a concentration-dependent manner. It inhibits the production of IL-2 in T cell hybridoma cells expressing an MBP (85-99)-specific T cell receptor derived from a patient with multiple sclerosis. MBP peptide antagonist also delays MBP (85-99)-induced experimental autoimmune encephalomyelitis (EAE) onset and reduces EAE symptom severity in double-transgenic humanized mice expressing human HLA-DR2 and MBP (85-99)-specific T cell receptor antigen in a model of MS when administered at a dose of 100 µg/animal.
保存温度:
-20
运输温度:
-20
预期分子量:
1543.8
产品形式:
A solid
有效期:
1460
纯度:
≥98%
分子式:
C70H114N18O21 • XCF3COOH
上一个:BimS BH3 (51-76) (human) (trifluoroacetate salt)
下一个:GluR2 (831-842) (human, mouse, rat) (trifluoroacetate salt)
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