官网链接
折扣/货期| 货号：AG-40B-0169-C010 | 规格：10 ug | 目录价：￥3360 |
产品详情
产品名称:
IL-38 (aa 20-152) (human) (rec.) (His)
别名:
Interleukin-38; Interleukin-1 Family Member 10; IL-1F10
产品描述:
IL-38 (IL-1F10) belongs to the IL-1 family of proteins. IL-38 is expressed in heart, placenta, fetal liver, spleen, thymus and tonsil. The expression in a variety of immune tissues and similarity to IL-1Ra suggest a role of IL-38 in the inflammatory response. It has been reported that removal of the N-terminus domain of the interleukins of the IL-1F family such as IL-1F5 / 6 / 8 or 9 (also called IL-36Ra, IL-36alpha, IL-36beta or IL-36gamma) is important to increase their biological activity. Recently it has been shown that IL-38 is N-terminally processed and secreted by apoptotic cells. Released processed IL-38 (20-152) binds to the receptor Interleukin-1 receptor accessory protein-like 1 (IL1RAPL1; TIGIRR-2) at the surface of macrophages. Processed IL-38-activated IL1RAPL1 reduces the production of IL-6 leading to inflammation attenuation. IL-38 is unregulated during some autoimmune diseases such as Systemic Lupus Erythematosus.
宿主来源:
E. coli
产品浓度:
After reconstitution:for 10µg size: 0.1mg/mlfor 100µg size: 1 mg/ml
保存温度:
-20°C
运输温度:
BLUE ICE
预期分子量:
~16kDa
产品形式:
solid
存储溶液:
Lyophilized. Contains PBS.
有效期:
Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
产地:
瑞士
纯度:
>95% (SDS-PAGE)
内毒素水平:
<0.01EU/µg purified protein (LAL test).
上一个:IL-33 (oxidation resistant) (human) (rec.) (His)
下一个:HpARI (Alarmin Release Inhibitor) (rec.) (His) MultiPack
您可能感兴趣的产品
Human IL1F5 protein, His tag
货号：GTX68383-pro
Human VEGF165 protein, His tag
货号：GTX67937-pro
Rat IL6 protein, His tag (active)
货号：GTX67073-pro
Human IL6 protein, His tag (active)
货号：GTX67071-pro
Human IL2 protein (active)
货号：GTX67060-pro
Feline IL2 protein, His tag (active)
货号：GTX66898-pro
Human IL1 Receptor 1 protein, human IgG1 Fc tag (active)
货号：GTX65662-pro
Human IL1F10 protein, His tag
货号：GTX57238-pro
促销活动
精品推荐
相关产品推荐
IL-2 (mouse):Fc (mouse) (rec.) (non-lytic)
货号：CHI-MF-12002-C010
IL-4 (mouse):Fc (mouse) (rec.) (non-lytic)
货号：CHI-MF-12004-C010
IL-6 (mouse):Fc (mouse) (rec.) (non-lytic)
货号：CHI-MF-12006-C050
IL-10 (mouse):Fc (mouse) (rec.) (non-lytic)
货号：CHI-MF-12010-C010
IL-21 (mouse):Fc (mouse) (rec.) (non-lytic)
货号：CHI-MF-12021-C050
IL-21R (mouse):Fc (mouse) (rec.) (non-lytic)
货号：CHI-MF-12021R-C025
