IL-36gamma (aa 18-169) (human) (rec.) (untagged) MultiPack-细胞因子、趋化因子与生长因子-ELISA_抗体_蛋白_核苷酸

首页产品中心细胞因子、趋化因子与生长因子

IL-36gamma (aa 18-169) (human) (rec.) (untagged) MultiPack

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-40B-0166-3010	规格：3 x 10 ug	目录价：￥4560
货号：AG-40B-0166-C010	规格：10 ug	目录价：￥2280

产品详情

产品名称:

IL-36gamma (aa 18-169) (human) (rec.) (untagged) MultiPack

别名:

Interleukin-36gamma Interleukin-1 Family Member 9; IL-1F9

产品描述:

IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1 and are inhibited by IL-36Ra. The expression of IL-36 cytokines has been shown to occur at different sites including the lung and skin and can be derived from diverse cell types including keratinocytes, bronchial epithelium as well as macrophages, monocytes and different T cell subsets. IL-36 family members induce the production of proinflammatory cytokines, including IL-12, IL-1beta, IL-6, TNF-alpha and IL-23 in BMDC and CD4 T cells, thus promoting neutrophil influx, dendritic cell (DC) activation, polarization of T helper type 1 (Th1) and IL-17-producing T cells (alphabeta T cells and gammadelta T cells) and keratinocyte proliferation. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination. IL-36gamma is also induced in the lung in various models of asthma and can be produced by bronchial epithelial cells in response to viral infection, smoke or inflammatory cytokines.

宿主来源:

E. coli

产品浓度:

0.1mg/ml after reconstitution

保存温度:

-20°C

运输温度:

BLUE ICE

预期分子量:

~17kDa

产品形式:

solid