九游会j9网站首页,j9九游会首页登录,j9九游会ag真人官网

深圳九游会j9网站首页有限公司 a1

IL-33 (human) (rec.) (His)
品牌：Adipogen
货号：AG-40A-0042-C010 规格：10 ug 目录价：￥1560
货号：AG-40A-0042-C050 规格：50 ug 目录价：￥4680
产品详情
产品名称:
IL-33 (human) (rec.) (His)
别名:
Interleukin-33; IL-1F11; NF-HEV
产品描述:
Interleukin-33 (IL-33; HF-NEV; IL-1F11), a member of the IL-1 family of cytokines, is expressed by many cell types following pro-inflammatory stimulation and is thought to be released on cell lysis. The 30kDa human IL33 is converted by CASP1 to a 18kDa protein. IL33 binds to and signals through ST2 (IL1R1) and its stimulation recruits MYD88, IRAK, IRAK4, and TRAF6, followed by phosphorylation of ERK1 (MAPK3)/ERK2 (MAPK1), p38 (MAPK14), and JNK. The ability of IL-33 to target numerous immune cell types, like Th2-like cells, mast cells, and B1 cells, and to induce cytokine and chemokine production underlines its potential in influencing the outcome of a wide range of diseases, such as arthritis, asthma, atopic allergy & anaphylaxis, cardiovascular disease/atherosclerosis, nervous system diseases, and sepsis.
宿主来源:
E. coli
靶标/特异性:
Binds to human ST2.
产品浓度:
1mg/ml
保存温度:
-20°C
运输温度:
BLUE ICE
预期分子量:
~18kDa (SDS-PAGE)
产品形式:
liquid
存储溶液:
Liquid. 0.2µm-filtered solution in 55mM TRIS-Cl, pH 8.2, containing 150mM NaCl.
有效期:
Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
产地:
瑞士
纯度:
>90% (SDS-PAGE)
生物活性:
Activates human ST2-dependent NF-kappaB pathway.
内毒素水平:
<1EU/µg purified protein (LAL test; Lonza).
在线留言
咨询类型
联系人
*
联系方式
*
单位名称
*
咨询内容
*
九游会j9网站首页