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折扣/货期| 货号：CHI-AG-40A-0038-C010 | 规格：10 ug | 目录价：￥3360 |
产品详情
产品名称:
IL-23 (human) (rec.)
别名:
Interleukin-23
产品描述:
Interleukin-23 (IL-23) is a heterodimeric cytokine and a member of the IL-12 family involved in innate and adaptive immunity. It is composed of the IL-12 p40 chain covalently linked to p19, a chain related to the IL-12 p35 subunit. IL-23 signals through the IL-23 receptor complex, which is composed of the IL-12Rbeta1 chain and a gp130-like chain, IL-23R. Triggering of the IL-23 receptor complex leads to the activation of Tyk2, Jak2 and STAT1, 3 and 4. IL-23 induces IFN-gamma production, Th1 cell differentiation, and activation of the antigen-presenting functions of dendritic cells. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and important for tumorigenesis.
宿主来源:
HEK 293 cells
保存温度:
-20°C
运输温度:
BLUE ICE
预期分子量:
~70kDa (SDS-PAGE)
产品形式:
solid
存储溶液:
Lyophilized from 0.2µm-filtered solution in PBS.
有效期:
Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
产地:
瑞士
纯度:
>90% (SDS-PAGE)
内毒素水平:
<0.06EU/µg purified protein (LAL test; Lonza).
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