IL-21 (human) (rec.) (untagged)-细胞因子、趋化因子与生长因子-ELISA_抗体_蛋白_核苷酸

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IL-21 (human) (rec.) (untagged)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：CHI-HR-20621-C010	规格：10 ug	目录价：￥3220
货号：CHI-HR-20621-C050	规格：50 ug	目录价：￥9100

产品详情

产品名称:

IL-21 (human) (rec.) (untagged)

别名:

Interleukin-21

产品描述:

Interleukin-21 (IL-21) is a key factor in the transition between innate and adaptive immune responses secreted by activated T cells. The IL-21 receptor (IL-21R) is expressed in lymphoid tissue, in particular by NK, B, T and dendritic cells, macrophages and endothelial cells. Recent evidence suggests that IL-21 plays a supportive role in the proliferation of T and B cells and influences the cytolytic activity of natural killer cells. IL-21 has been shown to up-regulate genes associated with innate immunity and to inhibit the differentiation of naïve T helper cells. IL-21 specifically inhibits IFN-gamma production from developing TH1 cells and is preferentially expressed by TH2 cells. Furthermore IL-21 has been identified as a growth and survival factor for human myeloma cells. IL-21/IL-21R interactions have a unique role in sequentially activating both innate and adaptive immune responses against poorly immunogenic tumors, leading to tumor rejection that is perforin dependent but IFN-gamma independent.

宿主来源:

E. coli

保存温度:

-80°C

运输温度:

BLUE ICE

预期分子量:

~17kDa (SDS-PAGE)

产品形式:

solid

存储溶液:

Lyophilized from 0.2µm-filtered solution in PBS.