官网链接
折扣/货期| 货号：GTX03075 | 规格：1pair | 目录价：￥9300 |
产品详情
产品名称:
IL12B / IL12 p40 ELISA pair [C15.6/C17.8]
别名:
interleukin 12B , CLMF , CLMF2 , IL-12B , IMD28 , IMD29 , NKSF , NKSF2
反应种属:
Mouse
实验应用:
ELISA, Sandwich ELISA
靶标/特异性:
GTX02953 (C15.6) is able to detect native and recombinant mouse p40 subunit of IL-12 and IL-23. In combination with GTX02954-02 (C17.8), it recognizes p40 monomer, p40 homodimer, IL-12 p70 heterodimer (p40 + p35), and IL-23 heterodimer (p40 + p19).
克隆号:
产品浓度:
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
37
产品形式:
Liquid
产地:
美国
功能与背景:
This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children. [provided by RefSeq, Jul 2008]
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