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    Human TNNI1 protein, His tag
    品牌:GeneTex
    货号:GTX67892-pro 规格:100μg 目录价:¥4100
    产品详情
    产品名称:
    Human TNNI1 protein, His tag
    别名:
    troponin I1, slow skeletal type , SSTNI , TNN1
    克隆号:
    偶联:
    Unconjugated
    产品浓度:
    1 mg/ml (Please refer to the vial label for the specific concentration.)
    表达系统:
    E. coli
    保存温度:
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
    运输温度:
    dry ice
    产品形式:
    Liquid
    存储溶液:
    20mM Tris-HCl, 0.4M Urea, 10% Glycerol, no preservative.
    产地:
    美国
    功能与背景:
    Troponin proteins associate with tropomyosin and regulate the calcium sensitivity of the myofibril contractile apparatus of striated muscles. Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. The TnI-fast and TnI-slow genes are expressed in fast-twitch and slow-twitch skeletal muscle fibers, respectively, while the TnI-cardiac gene is expressed exclusively in cardiac muscle tissue. This gene encodes the Troponin-I-skeletal-slow-twitch protein. This gene is expressed in cardiac and skeletal muscle during early development but is restricted to slow-twitch skeletal muscle fibers in adults. The encoded protein prevents muscle contraction by inhibiting calcium-mediated conformational changes in actin-myosin complexes. [provided by RefSeq, Jul 2008]
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