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Human RASSF1 protein, His tag
品牌：GeneTex
货号：GTX68233-pro 规格：100μg 目录价：￥4100
产品详情
产品名称:
Human RASSF1 protein, His tag
别名:
Ras association domain family member 1 , 123F2 , NORE2A , RASSF1A , RDA32 , REH3P21
克隆号:
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
表达系统:
E. coli
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
dry ice
产品形式:
Liquid
存储溶液:
20mM Tris-HCl, 0.4M Urea, 10% Glycerol, no preservative.
产地:
美国
功能与背景:
This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, May 2011]
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