货号:GTX67136-pro | 规格:10μg | 目录价:¥4100 |
产品详情
产品名称:
Human PPP1A protein, His tag (active)
别名:
protein phosphatase 1 catalytic subunit alpha , PP-1A , PP1A , PP1alpha , PPP1A
实验应用:
Functional Assay
克隆号:
偶联:
Unconjugated
产品浓度:
0.2 mg/ml (Please refer to the vial label for the specific concentration.)
表达系统:
E. coli
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
dry ice
产品形式:
Liquid
存储溶液:
50mM Tris-HCl, 200mM NaCl, 50% Glycerol, 1mM DTT, 0.1mM PMSF, 1mM MnCl₂, no preservative.
产地:
美国
功能与背景:
The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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