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    Human MBD3 protein, His tag
    品牌:GeneTex
    货号:GTX68540-pro 规格:50μg 目录价:¥5500
    产品详情
    产品名称:
    Human MBD3 protein, His tag
    别名:
    methyl-CpG binding domain protein 3
    克隆号:
    偶联:
    Unconjugated
    产品浓度:
    0.25 mg/ml (Please refer to the vial label for the specific concentration.)
    表达系统:
    E. coli
    保存温度:
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
    运输温度:
    dry ice
    产品形式:
    Liquid
    存储溶液:
    20mM Tris-HCl, 200mM NaCl, 40% Glycerol, 1mM DTT, 1mM EDTA, no preservative.
    产地:
    美国
    功能与背景:
    DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. This gene belongs to a family of nuclear proteins which are characterized by the presence of a methyl-CpG binding domain (MBD). The encoded protein is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. Unlike the other family members, the encoded protein is not capable of binding to methylated DNA. The protein mediates the association of metastasis-associated protein 2 with the core histone deacetylase complex. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
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