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折扣/货期| 货号：GTX136910-pro | 规格：500μg | 目录价：￥2300 |
产品详情
产品名称:
Human EGF protein (active)
别名:
epidermal growth factor , HOMG4 , URG
产品描述:
Epidermal Growth Factor (EGF) is a 53-a.a. peptide cleaved from a 1207 a.a. transmembrane glycoprotein precursor. Its binding to the EGF receptor (EGFR) affects cell proliferation and differentiation via downstream effectors.
实验应用:
Functional Assay
克隆号:
偶联:
Unconjugated
产品浓度:
表达系统:
E. Coli
保存温度:
Store at 4ºC or below. After reconstitution, keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. For long-term storage after reconstitution, aliquot and store at -70ºC or below. Do not vortex.
运输温度:
4°C
产品形式:
Lyophilized powder
存储溶液:
Reconstitute with distilled water to 0.1 mg/ml. Lyophilized from 50mM PBS, 100mM NaCl, 5% Trehalose, no Preservative.
产地:
美国
功能与背景:
This gene encodes a member of the epidermal growth factor superfamily. The encoded preproprotein is proteolytically processed to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding with high affinity to the cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]
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