货号:GTX66973-pro | 规格:100μg | 目录价:¥5500 |
产品详情
产品名称:
Human DUSP10 protein, His tag (active)
别名:
dual specificity phosphatase 10 , MKP-5 , MKP5
实验应用:
Functional Assay
克隆号:
偶联:
Unconjugated
产品浓度:
0.25 mg/ml (Please refer to the vial label for the specific concentration.)
表达系统:
E. coli
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
dry ice
产品形式:
Liquid
存储溶液:
20mM Tris-HCl, 200mM NaCl, 50% Glycerol, 2mM DTT, no preservative.
产地:
美国
功能与背景:
Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAP kinase superfamily, which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAP kinases, different tissue distribution and subcellular localization, and different modes of expression induction by extracellular stimuli. This gene product binds to and inactivates p38 and SAPK/JNK. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
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