货号:22733 | 规格:50 µg | 目录价:¥3388 |
产品详情
产品名称:
HOP (human recombinant)
别名:
Hsp70/Hsp90 Organizing Protein|Stress-Induced Phosphoprotein
产品描述:
HOP (Hsp70/Hsp90 Organizing Protein), also known as Stress-Induced Phosphoprotein 1 (STI1 or STIP1), acts as a co-chaperone to reversibly form a complex with Hsp70 and Hsp90 to assist in transfer of proteins between Hsp70 and Hsp90. The three tetratricopeptide repeat domains (TPR1, TPR2a, and TPR2b) act as binding regions, with TPR1 and TPR2B binding to Hsp70 and TPR2A binding to Hsp90. {39121} Highly conserved in Eukaryotes, it is closely related to the yeast STI1. HOP is both a nuclear and cytoplasmic protein, capable of travel between both. {39122} HOP has also been found to interact with several other proteins/complexes, including but not limited to: Hsc70, Hsp90α, Hsp90β, PACRG, METTL21B, FLCN, FNIP1, and FNIP2. {39123,39124,39125,39126,39127}
保存温度:
-80
运输温度:
-80
产品形式:
50 mM HEPES, pH 8.0, with 150 mM sodium chloride
有效期:
365
纯度:
≥95% as estimated by SDS-PAGE
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