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折扣/货期| 货号：10261 | 规格：1 mg | 目录价：￥7588 |
产品详情
产品名称:
Histone H2A (Xenopus, recombinant)
产品描述:
Histone H2A is a core histone that forms a dimer with histone H2B.{46631} Two histone H2A/H2B dimers form an octameric nucleosome with a histone H3/H4 tetramer, around which DNA wraps, allowing it to be condensed. Histone H2A can be post-translationally modified via methylation of the arginine at position 3 by protein arginine methyltransferase 1 (PRMT1), PRMT5, or PRMT6, which is associated with both transcriptional activation and repression.{46198} When methylated by PRMT7, it is associated with DNA damage repair. The arginine residue at position 3 of histone H2A is also subject to citrullination by protein arginine deiminase 4 (PAD4). Histone H2A is ubiquitinated by ubiquitin-specific protease 12 (USP12) during the gastrula stage of Xenopus development.{65096} The post-translational modifications on histone H2A vary between each stage of Xenopus development and are enriched on nucleosomes in Xenopus embryos that contain both active and repressive histone modifications.{65097} Cayman’s Histone H2A (Xenopus, recombinant) protein can be used as a substrate for enzyme activity assays, as well as for Western blot (WB) applications.
保存温度:
-80
运输温度:
-80
产品形式:
A lyophilized powder
有效期:
365
纯度:
≥95% estimated by SDS-PAGE
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