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折扣/货期| 货号：34768 | 规格：100 µg | 目录价：￥3136 |
产品详情
产品名称:
Hepcidin-25 (trifluoroacetate salt)
别名:
H-DTHFPICIFCCGCCHRSKCGMCCKT-OH
产品描述:
Hepcidin-25 is a peptide hormone that regulates iron homeostasis and has antibacterial activity.{64348} It is predominantly synthesized by hepatocytes and secreted into the circulation. Hepcidin-25 binds to ferroportin, a membrane-bound iron exporter expressed by macrophages, enterocytes, and hepatocytes, inducing ferroportin internalization and degradation, which increases intracellular iron levels and decreases dietary iron absorption and plasma iron levels. It is bactericidal against multidrug-resistant clinical isolates of Gram-negative and Gram-positive bacteria, including P. aeruginosa, E. coli, K. pneumoniae, S. aureus, S. epidermidis, and E. faecium, when used at concentrations ranging from 6.25 to 50 µg/ml.{64349} Serum hepcidin-25 levels are increased in patients with chronic kidney disease (CKD).{64350}
保存温度:
-20
运输温度:
-20
预期分子量:
2789.4
产品形式:
A lyophilized powder
有效期:
1460
纯度:
≥95%
分子式:
C113H170N34O31S9 • XCF3COOH
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