官网链接
折扣/货期| 货号：10782 | 规格：100 µg | 目录价：￥6048 |
产品详情
产品名称:
Gcn5 (human, recombinant)
别名:
General control of amino acid synthesis protein 5-like 2|KAT2A|Lysine acetyltransferase 2A|STAF97
产品描述:
Gcn5 and PCAF are highly homologous members of the Gcn5-related N-acetyltransferase (GNAT) superfamily of N-acetyltransferases involved in histone acetylation.{20191} Gcn5 and PCAF contain a highly conserved central core with divergent N- and C-terminal ends.{20189} Gcn5/PCAF are enzymatic subunits that exist in a mutually exclusive manner as part of the mammalian SAGA and ATAC complexes.{20187,20188} Recombinant Gcn5 preferentially acetylates lysine 14 on histone H3 in vitro. Recombinant Gcn5 alone is unable to acetylate nucleosomal core histone substrates. Acetylation of the nucleosomal histones requires that Gcn5 be a part of either the multisubunit SAGA or ATAC protein complexes.{20190} The multisubunit Gcn5/PCAF-containing complexes have a broad substrate specificity, including H3K9, H3K18, H4K8, and H4K16, as well as additional sites on histone H2B.{20187}
保存温度:
-80
运输温度:
-80
产品形式:
50 mM Tris, pH 8.0, with 150 mM sodium chloride and 20% glycerol
有效期:
730
纯度:
≥50% estimated by SDS-PAGE
您可能感兴趣的产品
Human Aldolase C protein
货号：GTX67212-pro
Human Sorbitol Dehydrogenase protein (active)
货号：GTX67160-pro
Human Fumarate hydratase protein (active)
货号：GTX66998-pro
beta Galactosidase protein
货号：GTX04676-pro
Human Lysozyme protein (active)
货号：GTX03701-pro
Human Flavin reductase protein
货号：GTX67254-pro
Human Aspartoacylase protein
货号：GTX67242-pro
Human Aldolase C protein (active)
货号：GTX66923-pro
促销活动
