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折扣/货期| 货号：AG-40B-0137-3010 | 规格：3 x 10 ug | 目录价：￥2400 |
| 货号：AG-40B-0137-C010 | 规格：10 ug | 目录价：￥1200 |
产品详情
产品名称:
FGF-1 (human) (rec.) (untagged) MultiPack
别名:
Fibroblast Growth Factor 1; Acidic Fibroblast Growth Factor; Endothelial Cell Growth Factor; ECGF; Heparin-binding Growth Factor 1; HBGF-1
产品描述:
Fibroblast growth factors (FGFs) constitute a family of heparin-binding polypeptides involved in the regulation of biological responses such as growth, differentiation and angiogenesis. The biological effects of FGFs are mediated by four structurally related receptor tyrosine kinases denoted FGFR1, FGFR2, FGFR3 and FGFR4. FGF-1 [FGF-acidic; ECGF; HBGF-1] is a powerful mitogen of cells of mesodermal, ectodermal and endodermal origin. FGF-1 association with heparan sulfate is a prerequisite for activation of FGF receptors. FGF-1 plays a role in various stages of development and morphogenesis as well as in angiogenesis and wound healing processes. Recent data indicate a role of FGF-1 in inflammation and obesity. FGF-1 is selectively induced in fat cells by high-fat diet feeding and established the PPARgamma-FGF-1 axis as a critical pathway that regulates adipose tissue remodeling.
宿主来源:
E. coli
产品浓度:
0.1mg/ml after reconstitution
保存温度:
-20°C
运输温度:
BLUE ICE
预期分子量:
~16kDa
产品形式:
solid
存储溶液:
Lyophilized. In PBS containing 0.2 mM DTT.
有效期:
Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
产地:
瑞士
纯度:
>95% (SDS-PAGE)
内毒素水平:
<0.01EU/µg purified protein (LAL test).
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