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折扣/货期| 货号：35487-10 mg | 规格：10 mg | 目录价：￥2422 |
| 货号：35487-25 mg | 规格：25 mg | 目录价：￥5348 |
| 货号：35487-5 mg | 规格：5 mg | 目录价：￥1344 |
| 货号：35487-50 mg | 规格：50 mg | 目录价：￥8022 |
产品详情
产品名称:
Davunetide (acetate)
别名:
AL-108|NAP|NAPVSIPQ
产品描述:
Davunetide is a neuroprotective peptide derived from activity-dependent neuroprotective protein (ADNP).{61972} It promotes tubulin assembly in a cell-free assay when used at a concentration of 1 fM.{61973} Davunetide (1 fM) protects against cytotoxicity induced by tetrodotoxin (Item Nos. 14963 | 14964), a peptide derived from amyloid-β (Aβ), or zinc in isolated neonatal cerebral cortical cells.{61972,61973} Intravitreal administration of davunetide (4 µl of a 100 µg/ml solution) inhibits increases in cleaved caspase-3 and decreases in Bcl-2 levels in retina isolated from streptozotocin-induced diabetic rats.{61974} It improves survival in a superoxide dismutase 1 mutant (SOD1G93A) transgenic mouse model of amyotrophic lateral sclerosis (ALS) when administered at 10 µg/animal.{61975} Davunetide prevents decreases in brain choline acetyltransferase (ChAT) activity and prevents memory deficits in the Morris water maze in an Apoe-/- mouse model of neurodegeneration.{61972}
保存温度:
-20
运输温度:
-20
预期分子量:
824.9
产品形式:
A solid
有效期:
1460
纯度:
≥98%
分子式:
C36H60N10O12 • XC2H4O2
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