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Cystatin C (human, recombinant)
品牌:Cayman
货号:31836-1 mg 规格:1 mg 目录价:¥38358
货号:31836-100 µg 规格:100 µg 目录价:¥5904
产品详情
产品名称:
Cystatin C (human, recombinant)
别名:
ARMD11|CYS3|Cystatin 3
产品描述:
Cystatin C, also known as cystatin 3, is a member of the cystatin superfamily of cysteine protease inhibitors encoded by CST3 in humans.{52848} It is a 120-amino acid peptide constitutively produced by all nucleated cells and, following signal peptide cleavage, is secreted in all tissues and body fluids.{52848,52847,52849} Cystatin C is an inhibitor of endogenous cysteine proteases, including cathepsins B, H, and L, as well as lysosomal proteinases, that regulates extracellular matrix (ECM) production and degradation.{52848} Due to the small size and basic pI of cystatin C, it is not freely filtered by the glomerulus and is reabsorbed by, and catabolized in, tubular epithelial cells, which facilitates its use as a biomarker of glomerular filtration rate (GFR). Serum and urine levels of cystatin C are increased in pediatric acute kidney injury patients.{52849} Cayman's Cystatin C (human, recombinant) protein can be used for enzyme activity assay applications. This protein consists of 131 amino acids and has a calculated molecular weight of 14.8 kDa.
保存温度:
-80
运输温度:
-80
产品形式:
Lyophilized from sterile PBS, pH 7.4
有效期:
365
纯度:
≥95% as determined by SDS-PAGE
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