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    CRAMP (140-173) (mouse) (trifluoroacetate salt)
    品牌:Cayman
    货号:37502-1 mg 规格:1 mg 目录价:¥854
    货号:37502-10 mg 规格:10 mg 目录价:¥6328
    货号:37502-5 mg 规格:5 mg 目录价:¥3374
    产品详情
    产品名称:
    CRAMP (140-173) (mouse) (trifluoroacetate salt)
    别名:
    Cathelicidin-related Antimicrobial Peptide|Cathelin-related Antimicrobial Peptide|mCRAMP
    产品描述:
    Cathelicidin-related antimicrobial peptide (CRAMP) (140-173) is a 34-amino acid peptide derivative of the 38-amino acid antimicrobial peptide CRAMP.{68335,68336} Mature CRAMP is formed from cleavage of the full-length peptide by cathepsin G.{68337,68338} CRAMP (140-173) (1 µg/ml) is active against K. pneumoniae in vitro.{68335} It decreases neutrophil infiltration of colonic epithelial and luminal surfaces in a porcine model of colitis when administered at a dose of 10 mg/kg.{68339} Ileal administration of CRAMP (140-173) (10 mg/kg) decreases disease severity and cecal bacterial burden and increases survival in a mouse model of C. difficile infection.{68340} However, intra-articular administration of CRAMP (140-173) (10 µl of 25 µM) also increases disease severity and induces synovitis in a mouse model of surgery-induced osteoarthritis.{68341}
    保存温度:
    -20
    运输温度:
    -20
    预期分子量:
    3878.7
    产品形式:
    A solid
    有效期:
    1460
    纯度:
    ≥95%
    分子式:
    C178H302N50O46 • XCF3COOH
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