货号:37502-1 mg | 规格:1 mg | 目录价:¥854 |
货号:37502-10 mg | 规格:10 mg | 目录价:¥6328 |
货号:37502-5 mg | 规格:5 mg | 目录价:¥3374 |
产品详情
产品名称:
CRAMP (140-173) (mouse) (trifluoroacetate salt)
别名:
Cathelicidin-related Antimicrobial Peptide|Cathelin-related Antimicrobial Peptide|mCRAMP
产品描述:
Cathelicidin-related antimicrobial peptide (CRAMP) (140-173) is a 34-amino acid peptide derivative of the 38-amino acid antimicrobial peptide CRAMP.{68335,68336} Mature CRAMP is formed from cleavage of the full-length peptide by cathepsin G.{68337,68338} CRAMP (140-173) (1 µg/ml) is active against K. pneumoniae in vitro.{68335} It decreases neutrophil infiltration of colonic epithelial and luminal surfaces in a porcine model of colitis when administered at a dose of 10 mg/kg.{68339} Ileal administration of CRAMP (140-173) (10 mg/kg) decreases disease severity and cecal bacterial burden and increases survival in a mouse model of C. difficile infection.{68340} However, intra-articular administration of CRAMP (140-173) (10 µl of 25 µM) also increases disease severity and induces synovitis in a mouse model of surgery-induced osteoarthritis.{68341}
保存温度:
-20
运输温度:
-20
预期分子量:
3878.7
产品形式:
A solid
有效期:
1460
纯度:
≥95%
分子式:
C178H302N50O46 • XCF3COOH
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