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折扣/货期| 货号：34435-1 mg | 规格：1 mg | 目录价：￥672 |
| 货号：34435-10 mg | 规格：10 mg | 目录价：￥4368 |
| 货号：34435-25 mg | 规格：25 mg | 目录价：￥10080 |
| 货号：34435-5 mg | 规格：5 mg | 目录价：￥3024 |
产品详情
产品名称:
Compstatin (trifluoroacetate salt)
别名:
ICVVQDWGHHRCT
产品描述:
Compstatin is a cyclic peptide inhibitor of complement activation (IC50s = 63 and 12 µM for the classical and alternative pathways, respectively).{64027,64024} It binds to complement component 3 (C3) and inhibits convertase-mediated cleavage of C3 to the complement activation products C3a and C3b.{64026} Compstatin (70 µM) inhibits the generation of C3a, activation of polymorphonuclear leukocytes (PMNs), and the binding of PMNs to the polymer surface in an isolated human whole blood model of extracorporeal circulation.{64025} In vivo, compstatin (21 mg/kg) inhibits the generation of C3b, C3c, and iC3b in a baboon model of heparin- and protamine-induced complement activation.{64028}
保存温度:
-20
运输温度:
-20
预期分子量:
1550.8
产品形式:
A solid
有效期:
1460
纯度:
≥98%
分子式:
C66H99N23O17S2 • XCF3COOH
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