货号:21942 | 规格:100 µg | 目录价:¥7630 |
产品详情
产品名称:
Citrullinated Vimentin (human, recombinant)
产品描述:
Vimentin is a cytoskeleton intermediate filament protein present in cells of mesenchymal origin, including leukocytes, endothelial cells, and smooth muscle cells.{42183} It is subject to citrullination by peptidyl arginine deiminase 2 (PAD2; Item No. 10785) under high calcium concentrations, which can occur during macrophage apoptosis.{31884} Citrullinated vimentin has been shown to have a role in the production of anti-citrullinated protein antibodies (ACPAs).{31884,31883,55252} ACPAs against citrullinated proteins, such as vimentin, are considered to be highly specific markers for rheumatoid arthritis and other autoimmune diseases.{31883,55252}
保存温度:
-80
运输温度:
-80
产品形式:
10 mM Tris, pH 8.0
有效期:
365
纯度:
≥55% estimated by SDS-PAGE
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