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折扣/货期| 货号：37625 | 规格：1 mg | 目录价：￥3136 |
产品详情
产品名称:
Citrullinated Vimentin (G147R) (R145 + R147) (140-160)-biotin Peptide
别名:
Biotin-GQGKS(Cit)L(Cit)DLYEEEMRELRRQ|Citrullinated VIM (G146R) (R144 + R146)-biotin
产品描述:
Citrullinated vimentin (G147R) (R145 + R147) (140-160)-biotin peptide is a biotinylated version of a di-citrullinated form of a mutant isoform of the cytoskeleton intermediate filament protein vimentin, vimentinG146R, which has been found in the synovial fluid of patients with rheumatoid arthritis.{55252} Vimentin is subject to citrullination by peptidyl arginine deiminase 2 (PAD2) under high calcium concentrations, which can occur during macrophage apoptosis.{64643,31884} Serum levels of immune complexes targeting citrullinated vimentin are increased in patients with rheumatoid arthritis and positive for anti-citrullinated protein antibodies (ACPAs).{66176} Serum and plasma levels of citrullinated vimentin are also increased in patients with lung cancer or idiopathic pulmonary fibrosis, respectively.{35094,35741} Cayman’s Citrullinated Vimentin (G147R) (R145 + R147) (140-160)-biotin Peptide is intended for use in the detection of autoantibodies against vimentinG146R citrullinated at R145 and R147.
保存温度:
-20
运输温度:
-20
产品形式:
A lyophilized peptide
有效期:
1095
上一个:Citrullinated Vimentin (R144) (139-159)-biotin Peptide
下一个:Citrullinated Histone H3 (R2 + R8 + R17) (2-22)-biotin Peptide
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