官网链接
折扣/货期| 货号：34877 | 规格：100 µg | 目录价：￥5040 |
产品详情
产品名称:
CD1d Extracellular Domain/β2-Microglobulin Complex (human, recombinant)
别名:
Antigen-presenting Glycoprotein CD1d|B2M|R3G1|β2-Microprotein
产品描述:
CD1d is a lipid antigen-presenting molecule and a member of the group II CD1 family expressed by humans and mice.{60764} It is composed of a heavy chain, a transmembrane region, and a short intracellular C-terminal tail.{60764} The heavy chain contains three extracellular domains that associate with the light-chain β2-microglobulin. It is expressed primarily by antigen-presenting cells.{60764,60765} CD1d is directly involved in the process of presenting lipid antigens to T cells and invariant natural killer T (iNKT) cells to induce an immune response, including the secretion of specific cytokines depending on the antigen presented. Activation of iNKT cells by CD1d presentation of α-galactosylceramide (α-GalCer) in a murine model of melanoma reduces the number of metastases, but only when bone marrow-derived dendritic cells (BMDCs) were used to prolong iNKT cell responses.{60766}
宿主来源:
HEK293 cells
保存温度:
-80
运输温度:
-80
产品形式:
50 mM Tris HCl, pH 8.0, 150 mM sodium chloride
有效期:
365
纯度:
≥90%
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